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原文摘录:Furthermore, studies have reported the ability of lycopene to
induce apoptosis by down-regulating the expression of antiapoptotic
proteins, including Bcl-2, BclXL, and surviving and by
up-regulating the expression of the pro-apoptotic proteins Bax,
Bad, and Bim and associated activation of caspases 8, 9, and 3
(Gupta et al., 2013a; Jeong et al., 2019).
参考文献:
Gupta, P., Bansal, M. P., and Koul, A. (2013a). Evaluating the effect of lycopene
from Lycopersicum esculentum on apoptosis during NDEA induced
hepatocarcinogenesis. Biochem. Biophys. Res. Commun. 434 (3), 479–485.
doi: 10.1016/j.bbrc.2013.03.099
Jeong, Y., Lim, J. W., and Kim, H. (2019). Lycopene inhibits reactive oxygen
species-mediated NF-kB signaling and induces apoptosis in pancreatic cancer
cells. Nutrients 11 (4), 762. doi: 10.3390/nu11040762
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