|
|
发表于 2015-3-25 22:58:03
|
显示全部楼层
这个文件是可以做过滤器的，格式跟OVID以前的格式类似，只是标识符发生了变化：
<1>
Accession Number
71801311
Authors
Kagan I. Lev S. Grinev M. Theilla M. Cohen J. Stein M. Silva V. Singer P.
Institution
(Kagan, Grinev, Theilla, Cohen, Silva, Singer) General Intensive Care Department, Institute for Nutrition Research, Beilinson Hospital, Israel
(Lev) General Intensive Care Department, Institute for Nutrition Research, Hasharon Hospital, Israel
(Stein) Trauma Unit, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel
Correspondence Address
I. Kagan, General Intensive Care Department, Institute for Nutrition Research, Beilinson Hospital, Israel
Title
Supplemental EPA and GLA in multiple trauma patients: A prospective randomized blinded study.
Source
Clinical Nutrition. Conference: 36th European Society for Clinical Nutrition and Metabolism, ESPEN Congress Geneva Switzerland. Conference Start: 20140906 Conference End: 20140909. Conference Publication: (var.pagings). 33 (pp S34), 2014. Date of Publication: September 2014.
Publisher
Churchill Livingstone
Subject Headings
*patient
*human
*European
*society
*nutrition
*metabolism
*multiple trauma
ventilated patient
membrane
enteric feeding
oxygenation
mortality
air conditioning
infection
statistical analysis
gas chromatograph
erythrocyte
Israel
diet
acute lung injury
caloric intake
hospital
injury scale
head injury
parenteral nutrition
length of stay
parameters
control group
extubation
statistical significance
calorimetry
calorie
analysis of variance
adult respiratory distress syndrome
fatty acid
Abstract
Rationale: Continuous enteral EPA/GLA administration was shown to improve oxygenation and length of ventilation in patients with acute lung injury and ARDS. We assessed this effect in multiple trauma (MT) ventilated patients. Methods: A PRCDBT recruited consecutively 120 MT ventilated patients that tolerated enteral feeding. Calorie target was defined according to indirect calorimetry. The study group S received a formula enriched in 4.1 g/L EPA and 5.5 g/L GLA (Oxepa, Abbott). The control group C received the formula similar without EPA, GLA (Pulmocare, Abbott). Demographic parameters, oxygenation at day 1, 4 and 7, Length Of Stay, Length Of Ventilation, mortality and new infection were noted. Erythrocytes fatty acids membrane composition was analyzed (gas chromatograph). Statistical analysis was performed with the SAS system and ANOVA multiple variable analysis. P values <0.05 were considered significant. Results: 51 patients were included in S and 49 in C. 20 patients were excluded (early extubation or parenteral nutrition). There was no significant difference in age, sex, head trauma, Injury Severity Score (42.3+/-18.3 vs 42.5+/-18.0) between the groups. PaO2/FIO2 did not show any improvement in S (no difference between the 2 groups). LOV (16+/-10 vs 19+/-15 days in S), ICU and hospital LOS (30+/-17 vs 36+/-26 days) and low mortality were not different. No difference in new organ failures or acquired infection was observed. There was an increase (p< 0.001) in membrane composition levels of EPA (0.9+/-0.9 day 1 to 1.5+/-0.7 day 4 and 2.2+/-1.0 day 7) and GLA (0.08+/-0.04 day1 to 0.1+/-0.03 day 4 and 0.13+/-0.05 at day 7) in S but not in C. LOS was related to calorie intake regardless of the nutrition regimen. Conclusion: In severely traumatized ventilated patients, addition of EPA/GLA in the enteral feeding diet is increasing the membrane composition in these FA but is not improving clinical outcome. Grant from Israel Defense Force.
ISSN
0261-5614
Language
English
Summary Language
English
Publication Type
Journal: Conference Abstract
Entry Week
201512
Date Delivered
20150304
Year of Publication
2014
Copyright
Copyright 2015 Elsevier B.V., All rights reserved.
|
|
发表于 2015-3-18 10:58:03
发表于 2015-4-2 15:18:45